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Prescription for ChangeThe Looming Crisis in Drug Development$
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Michael Kinch

Print publication date: 2016

Print ISBN-13: 9781469630625

Published to North Carolina Scholarship Online: May 2017

DOI: 10.5149/northcarolina/9781469630625.001.0001

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Bridging the Valley

Bridging the Valley

(p.252) Chapter Twelve Bridging the Valley
Prescription for Change

Michael Kinch

University of North Carolina Press

The withdrawal of large company support for early stage research, combined with shrinking Federal expenditures, has created a “Valley of Death” in drug discovery that creates both pressing challenges and extraordinary opportunities. This chapter details the opportunities that could be created by incentivizing new innovative and entrepreneurial research into novel medicines. Many “experiments” are currently under way to identify novel means of addressing the Valley of Death and successful examples include a partnership between Yale University and Gilead Sciences, a California biotechnology company. We also explore the potential and limitations of academia rising as a means to address the need for early-stage drug research and conclude the chapter and the book with the idea that the Federal government could play a key role were it to more actively and creatively function as both the largest source of public venture capital as well as the key regulator of new medicines.

Keywords:   National Institutes of Health, FDA, Public venture capital, Gilead Sciences

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